Disorders of Glucose Transporters René Santer GENERAL CONSIDERATIONS D-glucose and other monosaccharides are hy-drophilic substances that cannot easily cross the lipophilic bilayer of the cell membrane. Since carbohydrates…
Inherited Bleeding Disorders Amy L. Dunn, Shannon L. Meeks, and Thomas C. Abshire Inherited bleeding disorders are a heterogeneous group of conditions that lead to excessive hemorrhage. The…
Cancer Genetics and Biology David Malkin The unique biological features, the cell of origin, and the response to therapy of childhood cancers make them intriguing models with which…
Normal Structure and Function of the Gastrointestinal Tract Alan N. Mayer ANATOMY AND HISTOLOGY The gastrointestinal (GI) tract is a continuous tube beginning at the mouth and ending…
Abnormalities of the Lungs M. Grisel Galarza and Ilene R. S. Sosenko SIGNS OF RESPIRATORY DISTRESS Respiratory distress syndrome in the newborn (discussed in detail in Chapter 54)…
Brain Tumors and Spinal Tumors Kenneth J. Cohen and Ian F. Pollack Central nervous system (CNS) neoplasms are, as a group, the most common solid tumors of childhood,…
Chemotherapy and Radiation Therapy Peter C. Adamson and Larry E. Kun Over the last four decades of the 20th century, the cure rates for childhood cancer increased from…
Dental Emergency Care Howard L. Needleman and Brian Grove OROFACIAL TRAUMA EPIDEMIOLOGY Trauma to children’s teeth is a very common event.1 The prevalence of these injuries varies depending…
Physiologic Basis of Pulmonary Function Daniel J. Weiner The respiratory system is composed of many different cell and tissue types, including airways, lung parenchyma, respiratory muscles, nerves, and…
Calcium, Phosphorus, and Magnesium Metabolism Allen W. Root NORMAL MINERAL HOMEOSTASIS CALCIUM Calcium (Ca) is present largely (99%) in the skeleton as the hydroxyapatite crystal of calcium phosphate…
