PEDIATRICS

Infectious and Non-infectious Tumor-Like Lesions

Dec 20, 2017 by in PEDIATRICS Comments Off on Infectious and Non-infectious Tumor-Like Lesions

Pathological agent Lesion Site Morphology Bacteria Staphylococcus aureus Abscess Any, bone Cocci Gram + Streptococcus spp. Abscess Skin, any Cocci Gram + Mycobacteria tub. Tuberculoma Any any Granul. Patterns, Zielh+…

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General Considerations

Dec 20, 2017 by in PEDIATRICS Comments Off on General Considerations

Predisposing disease Tumors Neurofibromatosis type 1 (NF1 gene mutation) Neurofibroma, Schwannoma, MPNST, GIST Rhabdomyosarcoma Hereditary retinoblastoma (RB1 gene mutation) Bone and soft tissue sarcomas Antineoplastic treatment (radiotherapy, alkylating agents) Sarcomas…

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Blastemal Tumors

Dec 20, 2017 by in PEDIATRICS Comments Off on Blastemal Tumors

Fig. 4.1 Neuroblastoma . Poorly differentiated neuroblastoma . No neuropil. Elevated MKI. MGG Fig. 4.2 Neuroblastoma. Maturating neuroblastoma . Some larger cells with cytoplasm. MGG Fig. 4.3 Neuroblastoma. Neuropil and…

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Low-Grade Superficial Connective Tumors

Dec 20, 2017 by in PEDIATRICS Comments Off on Low-Grade Superficial Connective Tumors

Fig. 5.1 Desmoid fibromatosis . Long fascicular cohesive fragment of bland fibroblasts and scattered uniform fibroblasts, some with cytoplasmic processes, May-Grünwald Giemsa (MGG) Fig. 5.2 Desmoid fibromatosis. Loosely cohesive cluster…

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Round Cell Sarcomas

Dec 20, 2017 by in PEDIATRICS Comments Off on Round Cell Sarcomas

Fig. 3.1 (a) A low-power view of embryonal RMS featuring tissue fragments with stroma and numerous dissociated rhabdomyoblasts. (b) Two large tissue fragments containing stroma and tumor cells. (a) Giemsa,…

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Pediatric Tumors of the Central Nervous System: Cytopathology

Dec 20, 2017 by in PEDIATRICS Comments Off on Pediatric Tumors of the Central Nervous System: Cytopathology

Anatomic sites Main histopathological subtypes Posterior fossa (cerebellum, fourth ventricle and brainstem) Medulloblastoma Atypical teratoid/rhabdoid tumor (AT/RT) Pilocytic astrocytoma Ependymoma Brainstem diffuse glioma Cerebral hemispheres Ganglioglioma (temporal lobe) Pleomorphic xanthoastrocytoma…

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Miscellaneous Epithelial and Epithelial-like Tumors

Dec 20, 2017 by in PEDIATRICS Comments Off on Miscellaneous Epithelial and Epithelial-like Tumors

Fig. 7.1 UCNT, Regaud type , isolated tumor cells and inflammatory background, May-Grünwald Giemsa (MGG) Fig. 7.2 UCNT, Schminke type, spindle-shaped cells, Papanicolaou 7.1.3 Ancillary Techniques Immunocytochemistry (ICC) shows positivity…

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Non-round Cell Sarcomas

Dec 20, 2017 by in PEDIATRICS Comments Off on Non-round Cell Sarcomas

Fig. 6.1 Epithelioid sarcoma. Polymorphous epithelioid with rhabdoid features , May-Grünwald-Giemsa (MGG) Fig. 6.2 Epithelioid sarcoma . Polymorphous epithelioid cells , Papanicolaou Fig. 6.3 Epithelioid sarcoma. Epithelioid cells mimicking carcinoma…

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Lymphomas in Children and Adolescents

Dec 20, 2017 by in PEDIATRICS Comments Off on Lymphomas in Children and Adolescents

Fig. 9.1 Classical Hodgkin Lymphoma featuring one Reed-Sternberg cell surrounded by an inflammatory background. There are five eosinophils in the field. MGG ×60 RS cells may be bi-nucleated or may…

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Thyroid Tumors

Dec 20, 2017 by in PEDIATRICS Comments Off on Thyroid Tumors

Thyroid carcinomas Other thyroid tumors Papillary carcinoma Teratoma Follicular carcinoma Primary lymphoma and plasmacytoma Poorly differentiated carcinoma Ectopic thymoma Undifferentiated (anaplastic) carcinoma Angiosarcoma Squamous cell carcinoma Smooth muscle tumors Mucoepidermoid…

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