Paternal bias: The impact of not accounting for paternal confounders in reproductive epidemiological studies

Aug 21, 2020 by in GYNECOLOGY Comments Off on Paternal bias: The impact of not accounting for paternal confounders in reproductive epidemiological studies

Objective A growing number of researchers have recently discussed paternal factors as independent determinants of offspring health. For example, animal studies have shown that sperm carries an epigenetic cargo, allowing…

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Fetal cardiac remodeling and dysfunction is associated with both preeclampsia and fetal growth restriction

Aug 21, 2020 by in GYNECOLOGY Comments Off on Fetal cardiac remodeling and dysfunction is associated with both preeclampsia and fetal growth restriction

Background Preeclampsia and fetal growth restriction share some pathophysiologic features and are both associated with placental insufficiency. Fetal cardiac remodeling has been described extensively in fetal growth restriction, whereas little…

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Risks of cause-specific mortality in offspring of pregnancies complicated by hypertensive disease of pregnancy

Aug 21, 2020 by in GYNECOLOGY Comments Off on Risks of cause-specific mortality in offspring of pregnancies complicated by hypertensive disease of pregnancy

Background Fetal environment has a substantial influence on an individual’s health throughout their life course. Animal models of hypertensive disease of pregnancy have demonstrated adverse health outcomes among offspring exposed…

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