Anti–severe acute respiratory syndrome coronavirus 2 antibodies induced in breast milk after Pfizer-BioNTech/BNT162b2 vaccination

Jul 5, 2021 by in GYNECOLOGY Comments Off on Anti–severe acute respiratory syndrome coronavirus 2 antibodies induced in breast milk after Pfizer-BioNTech/BNT162b2 vaccination

Objective In December 2020, 2 lipid nanoparticle-formulated, nucleoside-modified messenger RNA–based vaccines received emergency use authorization by the US Food and Drug Administration, after their trials demonstrated 94% to 95% efficacy…

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Amniotic fluid interleukin 6 and interleukin 8 are superior predictors of fetal lung injury compared with maternal or fetal plasma cytokines or placental histopathology in a nonhuman primate model

Jul 5, 2021 by in GYNECOLOGY Comments Off on Amniotic fluid interleukin 6 and interleukin 8 are superior predictors of fetal lung injury compared with maternal or fetal plasma cytokines or placental histopathology in a nonhuman primate model

Background Intra-amniotic infection or inflammation is common in early preterm birth and associated with substantial neonatal lung morbidity owing to fetal exposure to proinflammatory cytokines and infectious organisms. Amniotic fluid…

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Detemir vs neutral protamine Hagedorn insulin for diabetes mellitus in pregnancy: a comparative effectiveness, randomized controlled trial

Jul 5, 2021 by in GYNECOLOGY Comments Off on Detemir vs neutral protamine Hagedorn insulin for diabetes mellitus in pregnancy: a comparative effectiveness, randomized controlled trial

Background Insulin detemir, being used increasingly during pregnancy, may have pharmacologic benefits compared with neutral protamine Hagedorn. Objective We evaluated the probability that compared with treatment with neutral protamine Hagedorn,…

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Black-White disparities in maternal in-hospital mortality according to teaching and Black-serving hospital status

Jul 5, 2021 by in GYNECOLOGY Comments Off on Black-White disparities in maternal in-hospital mortality according to teaching and Black-serving hospital status

Background Maternal mortality is higher among Black than White people in the United States. Whether Black-White disparities in maternal in-hospital mortality during the delivery hospitalization vary across hospital types (Black-serving…

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The role of the angle of progression in the prediction of the outcome of occiput posterior position in the second stage of labor

Jul 5, 2021 by in GYNECOLOGY Comments Off on The role of the angle of progression in the prediction of the outcome of occiput posterior position in the second stage of labor

Background Occiput posterior position is the most frequent cephalic malposition, and its persistence at delivery is associated with a higher risk of maternal and perinatal morbidity. Diagnosis and management of…

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Noninvasive prenatal screening in twin pregnancies with cell-free DNA using the IONA test: a prospective multicenter study

Jul 5, 2021 by in GYNECOLOGY Comments Off on Noninvasive prenatal screening in twin pregnancies with cell-free DNA using the IONA test: a prospective multicenter study

Background In singleton pregnancies, studies investigating cell-free DNA in maternal blood have consistently reported high detection rate and low false-positive rate for the 3 common fetal trisomies (trisomies 21, 18,…

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Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State

Jul 5, 2021 by in GYNECOLOGY Comments Off on Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State

Background Evidence is accumulating that coronavirus disease 2019 increases the risk of hospitalization and mechanical ventilation in pregnant patients and for preterm delivery. However, the impact on maternal mortality and…

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