GYNECOLOGY

Chapter 11 – Differences in Sex Development

Jun 12, 2023 by in GYNECOLOGY Comments Off on Chapter 11 – Differences in Sex Development

Summary Differences in Sex Development (DSD) is an umbrella term which covers conditions arising from a difference in observed and expected sex development. This could include karyotype, gonadal tissue, or…

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Chapter 9 – Rokitansky Syndrome

Jun 12, 2023 by in GYNECOLOGY Comments Off on Chapter 9 – Rokitansky Syndrome

Summary Rokitansky syndrome, or Mayer–Rokitansky–Küster–Hauser syndrome (MRKH) also known as Müllerian agenesis results from embryonic underdevelopment of the Müllerian duct, resulting in agenesis or atresia of the uterus, vagina or…

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Chapter 10 – Turner Syndrome

Jun 12, 2023 by in GYNECOLOGY Comments Off on Chapter 10 – Turner Syndrome

Summary TS is one of the most common sex chromosomal abnormalities, caused by complete or partial absence of one X chromosome in a phenotypic female. The most common features of…

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Chapter 8 – Primary Amenorrhoea and Delayed Puberty

Jun 12, 2023 by in GYNECOLOGY Comments Off on Chapter 8 – Primary Amenorrhoea and Delayed Puberty

Summary Female puberty, driven by the hypothalamic–pituitary–ovarian axis (HPO), sees numerous alterations in the body secondary to the rise in oestradiol concentration. Whilst the onset, tempo and sequence will vary…

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Chapter 7 – Müllerian Duct Anomalies

Jun 12, 2023 by in GYNECOLOGY Comments Off on Chapter 7 – Müllerian Duct Anomalies

Summary Congenital Müllerian anomalies occur in approximately 5% of females. Patients with simple anomalies may be asymptomatic and diagnosed incidentally during investigations for other gynaecological problems or in pregnancy. Others…

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