Atopic Dermatitis and Food Hypersensitivity
Key Points • About one third of children with moderate to severe atopic dermatitis (AD) are affected by food hypersensitivity. • A food allergy evaluation should be considered in children…
PEDIATRICS
Management of Food Allergy
Key Points • The management of food allergy entails dietary avoidance of the identified allergen to prevent chronic and acute food allergic reactions. • Allergen elimination diets should not be…
Oral Allergy Syndrome
Key Points • OAS is an IgE-mediated allergy that is due to cross-reactivity between pollens and homologous food proteins. • There is significant regional variation in OAS prevalence. • Several…
Allergic and Eosinophilic Gastrointestinal Disease
Key Points • IgE-mediated anaphylactic reactions to foods occur immediately after ingestion, are acute life-threatening events, and can cause gastrointestinal, pulmonary and cardiovascular symptoms. • Eosinophilic esophagitis (EoE), involving chronic…
Enterocolitis, Proctocolitis and Enteropathies
Key Points • A number of gastrointestinal food allergic disorders are not typically associated with food-specific IgE antibodies. • These dietary protein-induced cell-mediated disorders usually present in infancy. • There…
Prevention and Natural History of Food Allergy
Key Points • The rise in food allergy is more rapid than genetic deviation would allow and the current consensus is that environmental factors integrally linked to the ‘modern lifestyle’…
Evaluation of Food Allergy
Key Points • A food allergy is an adverse health effect arising from an immune response that occurs reproducibly on exposure to a given food, whereas a food intolerance is…
Approach to Feeding Problems in the Infant and Young Child
Key Points • Infants most often develop food allergies in the order of exposure (e.g. milk, egg, fish, vegetables, etc.). • The majority of infants and young children with food…
Mucosal Immunology: An Overview
Key Points • The gastrointestinal associated lymphoid tissue protects the vast surface of the gastrointestinal tract from pathogens while remaining tolerant to antigens from food and commensal microbiota. • Several…
New Directions in Asthma Management: A Tale of Two Cities
Key Points • Recent statistics show that asthma deaths and hospitalizations are decreasing, but there are still health disparities in that the African American/black population bears a heavier burden of…