Fig. 3.1 Low power examination of ovarian endometriotic cyst lined by epithelium and underlying stroma with remote hemorrhage represented by pigment-laden macrophages. H&E 20× Fig. 3.2 Ovarian stroma with endometrial-type…
Features of cytologic atypia 1. Loss of nuclear polarity 2. Irregular nuclear shape 3. Irregular nuclear contours 4. Vesicular chromatin 5. Hyperchromatic chromatin 6. Prominent nucleoli Reclassification of hyperplastic endometria…
Fig. 11.1 ASC-US (liquid-based preparation, LBP). (a) Mature squamous cells with nuclear enlargement, hyperchromasia, but even chromatin distribution. (b) ASC-US versus LSIL. Squamous cells with binucleation and nuclear enlargement: these…
Fig. 8.1 Serous EIC in a glandular pattern and flat pattern Fig. 8.2 Serous EIC, glandular pattern: cytologic features – a given case may variably show severe pleomorphism, hobnail nuclei,…
ISSVD 1976 ISSVD 1986 WHO 1994 ISSVD 2004 LASTa 2012 WHO 2014 Hyperplastic dystrophy with atypia, mild Vulvar intraepithelial neoplasia (VIN) I Mild dysplasia (VIN 1) – Low-grade squamous intraepithelial…
Fig. 12.1 Usual-type adenocarcinoma of the cervix, composed of tall columnar cells with significant nuclear enlargement, elongation, stratification, and hyperchromasia. The cytoplasm is rather dark, and intracytoplasmic vacuoles are absent…
Fig. 5.1 Microscopic features of complete hydatidiform mole (CHM). (a, b) Well-developed CHM with large hydropic villi and central cistern formation. Circumferential trophoblast hyperplasia is also present. (c, d) Early…
Vagina Cervix aLow-risk HPV aHigh-risk HPV aLow-risk HPV aHigh-risk HPV LSIL 81 18, 51 6, 11 18 42, 43, 54, 62, 67 56, 66 16, 66 16, 39, 52,…
Fig. 14.1 Overview of clinical management for precancerous cervical lesions. WHO World Health Organization, SIL squamous intraepithelial lesion, GIL glandular intraepithelial lesion, CIN1 cervical intraepithelial neoplasia grade 1, CIN2 cervical…
Fig. 6.1 Cartoon diagram highlights the anatomic site for tumor origin of uterine sarcoma Table 6.1 FIGO staging for uterine sarcomas (2009) [3] Stage Surgical-pathologic findings Leiomyosarcomas and endometrial stromal…
