The green tea polyphenol EGCG alleviates maternal diabetes–induced neural tube defects by inhibiting DNA hypermethylation

May 2, 2017 by in GYNECOLOGY Comments Off on The green tea polyphenol EGCG alleviates maternal diabetes–induced neural tube defects by inhibiting DNA hypermethylation

Background Maternal diabetes increases the risk of neural tube defects in offspring. Our previous study demonstrated that the green tea polyphenol, Epigallocatechin gallate, inhibits high glucose-induced neural tube defects in…

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Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis

May 2, 2017 by in GYNECOLOGY Comments Off on Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress, and apoptosis

Background Maternal type 1 and 2 diabetes mellitus are strongly associated with high rates of severe structural birth defects, including congenital heart defects. Studies in type 1 diabetic embryopathy animal…

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Racial-ethnic differences in midtrimester maternal serum levels of angiogenic and antiangiogenic factors

May 2, 2017 by in GYNECOLOGY Comments Off on Racial-ethnic differences in midtrimester maternal serum levels of angiogenic and antiangiogenic factors

Background Little is known about racial-ethnic differences in the distribution of maternal serum levels of angiogenic and antiangiogenic factors and their associations with early-onset preeclampsia. Objective We sought to investigate…

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Is a history of preeclampsia associated with an increased risk of a small for gestational age infant in a future pregnancy?

May 2, 2017 by in GYNECOLOGY Comments Off on Is a history of preeclampsia associated with an increased risk of a small for gestational age infant in a future pregnancy?

Background A history of preeclampsia is associated with an increased risk of subsequent preeclampsia, but it is unclear whether women with prior preeclampsia are at increased risk of having a…

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