Thymic Aplasia and T-Cell Disorder
Thymic Aplasia and T-Cell Disorder Yu-Lung Lau and Pamela Lee INTRODUCTION As detailed in chapter 49, host defense mechanisms against pathogens are defective in the newborn as a result of…
Initial Management of Metabolic Acidosis
Initial Management of Metabolic Acidosis Kristina Cusmano-Ozog and Kimberly Chapman DIAGNOSIS/INDICATION Metabolic acidosis in the neonate can have several causes, including increased acid intake from an exogenous source, increased endogenous…
Phagocytic Disorder
Phagocytic Disorder Yu-Lung Lau and Pamela Lee INTRODUCTION Phagocytosis is the process by which leukocytes internalize particles larger than 1 μm, such as microbes, apoptotic cells, and chemical substances.1 It…
G: Endocrine
Hypoglycemia in the Newborn Mark A. Sperling and Ram Menon INTRODUCTION This chapter outlines the epidemiology, etiology, pathophysiology, differential diagnosis, and management approach to the neonate with hypoglycemia, here defined…
Care of the Newborn With Ichthyosis
Care of the Newborn With Ichthyosis Jonathan A. Dyer and Mary Williams ICHTHYOSIS/MENDELIAN DISORDERS OF CORNIFICATION Clinical Findings Dermatologic dogma suggests differentiation of Mendelian disorders of cornification (MeDOC) subtypes is…
