Obgyn Key

Epidemiology of Childhood Cancer   Louise Parker   CANCER IS AN IMPORTANT CAUSE OF MORTALITY Childhood cancer is diagnosed in around 1 in 600 children under age 15 years. Nonetheless,…

Head and Neck Masses   David E. Tunkel and Jonathan A. Perkins   Head and neck masses commonly occur in young children, and the differential diagnosis for such masses is…

Clostridial Infections   Jose Zayas and Mobeen H. Rathore   CLOSTRIDIUM DIFFICILE Clostridium difficile is a spore-forming, obligate anaerobic, Gram-positive bacillus, which can spread via the fecal-oral route. The most…

Tumors   B. Stephens Richards   SOLITARY OSTEOCHONDROMA Osteochondroma, a cartilage-capped bony projection protruding from the surface of a bone, is the most common benign bone tumor. It reportedly accounts…

Pain Management and Sedation   Alan Farrow-Gillespie   “Although the world is full of suffering, it is also full of the overcoming of it.” —Helen Keller, 1880–1968.   The word…

Arboviruses   Jason Brophy and Elizabeth Lee Ford-Jones   Arboviruses (or arthropod-borne viruses) are a heterogeneous group of viruses that share the same usual route of entry into humans: via…

Systemic Lupus Erythematosus, Overlap Connective Tissue Diseases, and Mixed Connective Tissue Disease   Earl D. Silverman   SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) Systemic lupus erythematosus (SLE) represents the prototype of a…

Peroxisomal Disorders   David Valle, Gerald V. Raymond, and Stephen J. Gould   PEROXISOME BIOLOGY AND METABOLISM Peroxisomes are single membrane-bound or-ganelles present in all cells except for erythro-cytes. In…

Renal Tubular Disorders   Michel Baum   The glomeruli filter approximately 150 liters of ultrafiltrate daily that are delivered to the renal tubules. The renal tubules reabsorb organic solutes, salt,…

Hereditary Glomerulopathies   Clifford E. Kashtan   Hereditary disorders of the glomerulus are categorized on the basis of the demonstrated or predicted function(s) of the affected proteins. These are somewhat…