Fig. 5.1 Microscopic features of complete hydatidiform mole (CHM). (a, b) Well-developed CHM with large hydropic villi and central cistern formation. Circumferential trophoblast hyperplasia is also present. (c, d) Early…
Vagina Cervix aLow-risk HPV aHigh-risk HPV aLow-risk HPV aHigh-risk HPV LSIL 81 18, 51 6, 11 18 42, 43, 54, 62, 67 56, 66 16, 66 16, 39, 52,…
Fig. 14.1 Overview of clinical management for precancerous cervical lesions. WHO World Health Organization, SIL squamous intraepithelial lesion, GIL glandular intraepithelial lesion, CIN1 cervical intraepithelial neoplasia grade 1, CIN2 cervical…
Fig. 6.1 Cartoon diagram highlights the anatomic site for tumor origin of uterine sarcoma Table 6.1 FIGO staging for uterine sarcomas (2009) [3] Stage Surgical-pathologic findings Leiomyosarcomas and endometrial stromal…
Alterations P53 signature Serous tubal intraepithelial lesion (STIL) Serous tubal intraepithelial carcinoma (STIC) High-grade serous carcinoma P53 Mutated (LOH) Mutated Mutated (LOH) Mutated (LOH) BRCA1/BRCA2 Mutated/LOH Mutated/LOH/hypermethylated Genes (FISH) CCNE1…
Fig. 13.1 HSIL/CIN3 and atypical mitotic figure. Nuclear atypia extends through the full epithelial thickness without any cytoplasmic maturation in the superficial epithelial layers. Note the nuclear size and nuclear/cytoplasmic…
Fig. 2.1 (a) Ovarian cyst with surface involvement by friable papillary excrescences. They appear to cover most of the ovarian cyst surface. (b) The inner lining of the same ovarian…
Author # Complex atypical hyperplasia # Endometrial carcinoma Agents used Response rate (%) Median follow-up months (range) Ferenczy (1989) 20 0 MPA 50 5.5 years (2–7 years) Randall (1997) 17…
Agent (author) RCT design (N) Follow-up (years) Volume injected (mL)b Dry/improvedc Subjects requiring multiple treatments Durasphere [38] Multicenter Agent (176) 1 Agent: 4.83**** –/66 % 35 % Control (188) Control: 6.23**** –/66 %…
Fig. 9.1 Endometrial polyp occupying >50 of endometrial cavity Fig. 9.2 Submucosal Type I leiomyoma seen in right cornual region of postmenopausal women Physical Examination Careful gynecologic examination should be…
