. Inflammatory Bowel Disease
Inflammatory Bowel Disease Michael C. Stephens, Subra Kugathasan, and Thomas T. Sato Crohn disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel disease (IBD), are idiopathic,…
. Life Support Systems
Life Support Systems Julio Pérez Fontán The past three decades have seen immense advances in the technologies used to replace the functions of failing organs or systems. During…
. Acne and Other Disorders of the Pilosebaceous Unit
Acne and Other Disorders of the Pilosebaceous Unit Sara W. Dill and Bari B. Cunningham ACNE VULGARIS Acne vulgaris is one of the most common cutaneous disorders and…
. Immunizations
Immunizations Kristina A. Bryant Childhood immunizations represent one of the great public health achievements of the 20th and 21st centuries.1 Less than 250 years after Edward Jenner discovered…
. Myopathies
Myopathies Basil T. Darras MUSCULAR DYSTROPHIES Muscular dystrophies are an inherited group of primary diseases of muscle, characterized pathologically by muscle fiber degeneration and clinically by progressive muscle…
. Normal and Abnormal Hemostasis
Normal and Abnormal Hemostasis Janna M. Journeycake, Janet Yang, and Anthony K. C. Chan The hemostatic mechanism is a dynamic system that maintains the fluidity of blood, while…
. Optic Nerve Disorders
Optic Nerve Disorders John Roarty CONGENITAL ANOMALIES OPTIC NERVE HYPOPLASIA Optic nerve aplasia is extremely rare, and most often the diagnosis represents an extreme example of optic nerve…
. Cardiac Infections
Cardiac Infections Janet A. Stockheim and Stanford T. Shulman ENDOCARDITIS PATHOGENESIS Infective endocarditis (IE) in pediatric patients is often associated with an underlying congenital heart defect. However, structurally…