Prematurity

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Prematurity The circulatory adjustments and myocardial biochemical changes at birth and in the neonatal period are modified in direct relation to the degree of prematurity. The muscular coat of the…

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Fetal Cardiac Intervention

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Fetal Cardiac Intervention Improvements in prenatal diagnostic techniques have led to renewed interest in fetal cardiac intervention. The restoration of more normal flow and pressure relationships in the developing heart…

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Fetal Cardiology

Jul 1, 2016 by in OBSTETRICS Comments Off on Fetal Cardiology

Fetal Cardiology Extensive information about the circulatory physiology of the fetus and newborn has accumulated. The works of Barcroft (37), Dawes (38), Lind and associates (39), and Rudolph (40) should…

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Etiology

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Etiology Heart formation is a fantastic metamorphosis regulated by many sequences of genes. Given the remarkably complex orchestration of molecular and morphologic processes in formation of the heart, even small…

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Long-Term Survival

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Long-Term Survival This chapter focuses on infancy; however, discussions with parents concerning their newborn with a cardiac anomaly often quickly, and appropriately, move to the length and quality of life…

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Infant Mortality

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Infant Mortality Before aggressive intervention, Mitchell found that 2.3 of 1,000 live births died with cardiac problems in infancy (1). Infant cardiac mortality in developed countries has progressively declined over…

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Extracorporeal Membrane Oxygenation

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Extracorporeal Membrane Oxygenation Billie Lou Short In 1944 Kolff and Berk observed that blood became oxygenated as it passed through cellophane chambers of their artificial kidney membrane (1). This historic…

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Incidence

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Incidence The incidence of congenital heart disease detectable by routine clinical examination has been estimated to be 7.5 per 1,000 live births (1). The incidence of congenital heart anomalies in…

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Principles of Management of Respiratory Problems

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Principles of Management of Respiratory Problems William E. Truog Sergio G. Golombek Although the principles of management of respiratory disorders are constant, the techniques of treatment have become more complex…

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Bronchopulmonary Dysplasia

Jul 1, 2016 by in OBSTETRICS Comments Off on Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia Jonathan M. Davis Warren N. Rosenfeld Bronchopulmonary dysplasia (BPD) is a chronic lung disease that develops in newborn infants treated with oxygen and positive-pressure mechanical ventilation for a…

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