Objectives To evaluate the negative predictive value (NPV) of a rapid influenza diagnostic test (RIDT) in comparison with that of a real-time reverse transcription (rRT)-PCR test in pregnant women. Methods…
Objectives NDV3A-003 evaluated the safety, immunogenicity and efficacy of a vaccine, NDV-3A, to reduce the frequency and severity of infections in women with recurrent vulvovaginal candidiasis (RVVC). Methods NDV-3A is…
Objectives SYM-1219, a granule formulation of secnidazole, is being developed as a single oral dose therapy for bacterial vaginosis (BV). A previous study of SYM-1219 for the treatment of BV…
Objectives To evaluate the efficacy and safety of VT-1161, a potent, highly selective inhibitor of fungal CYP51, in treating women with a documented history of recurrent vulvovaginal candidiasis (RVVC). Methods…
Objectives Maternal sepsis is associated with high maternal morbidity and mortality. However, neonatal outcomes after maternal sepsis during pregnancy have not been described. The goal of this study was to…
Objectives Sepsis can develop in the peripartum period and increase the risk of maternal morbidity and mortality. The objective of this study is to determine if obstetrical complications are associated…
Objectives The objectives of this study were to identify the rate of postpartum endomyometritis (PPE) and determine modifiable risk factors for the development of PPE after cesarean delivery (CD) in…
Objectives Readmissions for surgical site infections (SSIs) are an increasing cost to healthcare systems. Cesarean SSIs in the United States range from 2% to 8% with the majority of those…
Objectives Our goals were to identify host innate immune genotypes associated with prevalent bacterial vaginosis (BV) and colonization with BV-associated bacteria (BVAB). Furthermore, we sought to characterize Lactobacillus colonization patterns…
Objectives Gardnerella vaginalis (GV) is highly prevalent in women with abnormal vaginal flora (Nugent score 4-6), yet have a preponderance of lactobacilli. Recent literature has suggested that specific clades (groupings…
