Objectives Secnidazole, a 5-nitroimidazole with a longer half-life, is structurally related to metronidazole and tinidazole. For treatment of bacterial vaginosis (BV), secnidazole is a suitable single-dose oral drug having a…
Objectives To characterize the biodiversity of the maternal microbiome during pregnancy and change in diversity over the course of pregnancy. Methods This study was conducted in two phases. In phase…
Objectives Cesarean delivery (CD) rates have risen steadily and until recently, the traditional surgical dogma of indwelling urethral catheters prior to CD was standard practice. While recent evidence suggests that…
Objectives Involvement in the criminal justice system has been associated with increased rates of sexually-transmitted diseases (STDs) and HIV at the individual and community levels. Studies of testing within jails…
Objectives Mycoplasma genitalium is associated with some STD syndromes, but whether it is a PID pathogen is unclear. We evaluated the role of MG in women with acute PID. Methods…
Objectives The echinocandin class of antifungal agents has not been considered for treatment of vulvovaginal candidiasis (VVC) because currently available echinocandins are limited to IV administration. This study investigated the…
Objectives The efficacy of intravaginally (IVG) administered CD101, a novel, long-acting and highly stable echinocandin formulated as a gel, was compared to marketed miconazole (MCZ) and nystatin (NYS) creams and…
Objectives Antenatal vaccination is an important aspect of obstetric care with guidelines shaped by ACOG and CDC. As of 2012, ACIP guidelines changed to include both Tdap and Influenza vaccines…
Objectives Opiate addiction in pregnancy has increased five-fold in the last decade and intravenous opioid use is associated with the acquisition of blood borne pathogens, such as hepatitis C virus…
Objectives Women having a Nugent score of 0-3 have a lower risk of HIV acquisition. Differences in the vaginal microbiota among races in the U.S. and among U.S. and African…
