Inherited blistering diseases Epidermolysis bullosa Epidermolysis bullosa (EB) is a family of rare, inherited disorders characterized by fragility of the skin and sometimes the mucosa in response to minor mechanical…

Introduction Newborn infant skin can manifest with an extraordinary array of conditions. Neonatal cutaneous findings may indicate transitory, benign processes such as erythema toxicum neonatorum, or may represent important harbingers…

Introduction Diagnostic and therapeutic procedures are a standard part of the evaluation and management of dermatologic conditions in neonates and infants. Performing procedures on younger children can be technically challenging,…

Introduction The skin simultaneously contacts a changing environment and provides closure for the body. It is a cellular and molecular interface, which plays a critical functional role in neurobehavior and…

Introduction The skin simultaneously contacts a changing environment and provides closure for the body. It is a cellular and molecular interface, which plays a critical functional role in neurobehavior and…

Introduction The skin of the neonate has a defective skin barrier relative to an older child. The neonate is extremely vulnerable to damage by environmental agents such as harsh detergents,…

Introduction The premature infant assumes the challenge of postnatal life, despite the immaturity of essential functions. Skin functions are primarily protective, and immaturity of the skin contributes to the vulnerability…

Introduction The skin of the newborn serves a pivotal role in the transition from the aqueous intrauterine environment to extrauterine terrestrial life and is integral to the vital functions of…