Ethics of Drug Research in Pediatric Populations Bruce A. Russell Sanford N. Cohen Virginia Delaney-Black Why Research on Children is Needed The majority of pharmacologic agents and pharmaceutical preparations currently…
Clinical Trials Involving Children: History, Rationale, Regulatory Framework, and Technical Considerations Steven Hirschfeld Brief History of Research Involving Children Children have been utilized to test new therapies for thousands of…
Adherence with Pediatric Medication Regimens Hakan Ergün Daniel A.C. Frattarelli Doreen Matsui Introduction In pharmacotherapy, the terms “compliance” and “adherence” are often used interchangeably, although the latter term is preferred…
Pharmacogenetics, Pharmacogenomics, and Pharmacoproteomics J. Steven Leeder Introduction It is readily accepted that genetic factors play an important role in influencing a child’s potential physical characteristics such as height, weight,…
Drug Metabolism and Disposition in Infants and Children Anders Rane The new regulatory framework for development of drugs for children has promoted the interest in pediatric pharmacology and left behind…
Clinical Pharmacokinetics in Infants and Children Edmund V. Capparelli Introduction Considerable growth has occurred in the number of new chemical and biologic treatments during the last 25 years. Appropriate use…
Drug Action and Therapy in the Infant and Child Ralph E. Kauffman Infancy and childhood extend from 2 months of age to the onset of puberty, which typically occurs at…
Introduction and Historical Perspectives Sumner J. Yaffe Jacob V. Aranda The following is an excerpt from the second edition of this book: The past several decades have witnessed a revolution…
INTRODUCTION Sensory impairment has a major effect on people’s lives: it affects them physically, socially, emotionally and financially. However, it is often a part of who they are, the way…
INTRODUCTION The past two decades have witnessed a dramatic change in maternity care. Despite these changes however, disabled women are still being marginalised in that their specific and individual needs…
