Growth Hormone and Bone
Fig. 8.1 Stimulation and action of intrinsic GH. GH is secreted in the pituitary gland and stimulated by hypothalamic hormones, such as GHRH and ghrelin, and is suppressed by somatostatin….
PEDIATRICS
Pediatric Bone Drugs: Calcium and Vitamin D
Fig. 10.1 Molecular structure of D2 and D3 Table 10.1 Food sources of vitamin D and calcium Dietary sources of calcium and vitamin D Calcium content Vitamin D content Breast…
Conclusion: Whither (or Wither?) the Pharmacology of Pediatric Bone?
Gordon L. Klein (ed.)Bone Drugs in Pediatrics2014Efficacy and Challenges10.1007/978-1-4899-7436-5_13 © Springer Science+Business Media New York 2014 13. Conclusion: Whither (or Wither?) the Pharmacology of Pediatric Bone? Gordon L. Klein1 (1) Department Orthopaedic Surgery and Rehabilitation, University…
Drug Development for Pediatric Diseases with Bone Loss
Fig. 3.1 Current model of osteoblast differentiation from stem cell. Ihh is the initiator of endochondral ossification. The Runx2-expressing bipotential progenitors can differentiate into either osteoblast or chondrocyte. Then cells…
Growth Hormone and Oxandrolone in Burned Children
Fig. 9.1 This figure illustrates the interlinking cascade of the growth hormone system throughout the body. GH growth hormone, GHBP GH binding protein, GH-S GH secretagogues, IGF-1 insulin-like growth factor-1,…
Developmental Pharmacokinetics: Drug Disposition Relative to Age
Patient age Total body watera Extracellular fluida Intracellular fluida <3-Month fetus 92 65 25 Term gestation 75 35–44 33 4–6 months 60 23 37 12 months 26–30 Puberty ~60 20…
Introduction
Gordon L. Klein (ed.)Bone Drugs in Pediatrics2014Efficacy and Challenges10.1007/978-1-4899-7436-5_1 © Springer Science+Business Media New York 2014 1. Introduction Gordon L. Klein1 (1) Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch and Shriners Burns…
Cardiology Laboratory
Cardiology Laboratory Timothy M. Hoffman BLOOD PRESSURE MEASUREMENT Accurate measurement of the blood pressure depends on selection of an appropriate cuff size of a sphygmomanometer. By convention, an appropriate cuff…
Syndromes Glossary
Syndromes Glossary Glossary 4p-syndrome —characterized by a round face, prominent nasal tip, polydactyly, and scoliosis. 5p-syndrome —characterized by macrocephaly; small mandible; long, thin fingers; short, big toes; and anorectal and…
Surgical Glossary
Surgical Glossary Glossary Aortopexy —procedure in which the aorta is approximated to the anterior thoracic wall; for the treatment of tracheomalacia. Bishop-Koop procedure —resection of a dilated loop of bowel…
