The familial focal epilepsies with onset in childhood or adolescence are classified according to the focus of seizure onset in different members of the same family. Seizure…
When rufinamide received its approval from the U.S. Food and Drug Administration (FDA) in November 2008, it was the first time that a new anticonvulsant medication was…
ETHOSUXIMIDE Ethosuximide (ESM) is a succinimide antiepileptic drug in clinical use since 1958 for a limited spectrum of seizure types, chiefly absence seizures, for which it remains…
INTRODUCTION There are many inborn errors of metabolism (IEMs) that cause disease in humans, and hundreds of these can produce encephalopathy and seizures. In fact, we now…
INTRODUCTION The International Classification of Epilepsies and Epileptic Syndromes (1) divides epilepsy, first, on the basis of whether the seizures are focal (localization-related epilepsies), generalized (originating at…
INTRODUCTION AND DEFINITION GEFS+ is an acronym for generalized epilepsy febrile seizures plus. It was defined by Scheffer et al in 1997 and was based upon a…
The search for mutated genes in several hereditary forms of epilepsy affecting infants and children has resulted in the identification of epileptic channelopathies (ie, epilepsies resulting from…
Important advances that enhance our understanding of the regulation of neuronal excitability in epilepsy and other brain functions have been made in molecular neurobiology. This research has…
, Dorothy L. Espelage2 and Leslie Carroll3 (1) Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA (2) University of Illinois at Urbana-Champaign, Champaign, IL, USA (3) Family Voices, Albuquerque,…
