Liver transplantation has been established as an effective treatment for children with end-stage liver disease for more than 30 years. Improving surgical techniques and the availability of new and more…
The first pediatric lung transplant was reported to the International Society for Heart and Lung Transplantation (ISHLT) in 1986 and, by June 2014, a total of 2090 pediatric lung transplants…
Advances in supportive care continue to lead to improvements in hematopoietic stem cell transplant (HSCT) outcomes. The 1-year transplant-related mortality (TRM) rate for children with acute leukemia and unrelated donor…
Each year more than 500 children undergo heart transplantation around the world, and infection is an important cause of morbidity and some mortality in these patients. The Registry of the…
Primary immunodeficiency diseases (PIDDs) can be defined as congenital disorders caused by an intrinsic molecular defect that alters the development or function of the immune system. As a consequence, patients…
Since chemotherapeutic agents were first administered for the treatment of malignancy, infection has been a cause of significant morbidity and mortality. Initial reports documented an infection-related mortality rate among patients…
This chapter provides an overview and approach to the diagnosis and management of the more common infections that occur in the fetus and newborn infant. Details about how each organism…
Bacterial Skin Infections Duha Al-Zubeidi Mary Anne Jackson Normal Skin Anatomy The epidermal skin layer provides the primary barrier to invasion by microorganisms and an interface between the body and the environment….
Illnesses resembling toxic shock syndrome (TSS) have been reported since 1927, but TSS was first defined as a disease in 1978 by Dr. James K. Todd and colleagues using criteria…
The eye can be affected by infections and infestations manifested as primary diseases or as part of systemic processes. Some infections are vision threatening, whereas others may have important implications…
