Oral Allergy Syndrome
Key Points • OAS is an IgE-mediated allergy that is due to cross-reactivity between pollens and homologous food proteins. • There is significant regional variation in OAS prevalence. • Several…
PEDIATRICS
Allergic and Eosinophilic Gastrointestinal Disease
Key Points • IgE-mediated anaphylactic reactions to foods occur immediately after ingestion, are acute life-threatening events, and can cause gastrointestinal, pulmonary and cardiovascular symptoms. • Eosinophilic esophagitis (EoE), involving chronic…
Enterocolitis, Proctocolitis and Enteropathies
Key Points • A number of gastrointestinal food allergic disorders are not typically associated with food-specific IgE antibodies. • These dietary protein-induced cell-mediated disorders usually present in infancy. • There…
Prevention and Natural History of Food Allergy
Key Points • The rise in food allergy is more rapid than genetic deviation would allow and the current consensus is that environmental factors integrally linked to the ‘modern lifestyle’…
Evaluation of Food Allergy
Key Points • A food allergy is an adverse health effect arising from an immune response that occurs reproducibly on exposure to a given food, whereas a food intolerance is…
Approach to Feeding Problems in the Infant and Young Child
Key Points • Infants most often develop food allergies in the order of exposure (e.g. milk, egg, fish, vegetables, etc.). • The majority of infants and young children with food…
Mucosal Immunology: An Overview
Key Points • The gastrointestinal associated lymphoid tissue protects the vast surface of the gastrointestinal tract from pathogens while remaining tolerant to antigens from food and commensal microbiota. • Several…
New Directions in Asthma Management: A Tale of Two Cities
Key Points • Recent statistics show that asthma deaths and hospitalizations are decreasing, but there are still health disparities in that the African American/black population bears a heavier burden of…
Asthma in Older Children: Special Considerations
Key Points • Failure of symptoms to respond to β-agonists and oral steroids should prompt consideration that the symptoms are not caused by asthma but by another process. • Cough…
Promoting Adherence and Effective Self-Management in Patients with Asthma
Key Points • Patients often take less than half of their prescribed controller medication, and surprisingly many stop taking their controller medication altogether after an initial filling at their pharmacy….
