Objectives To estimate the proportion of GBS-positive women with a history of penicillin allergy without anaphylaxis receiving appropriate intrapartum antibiotic prophylaxis. Methods Retrospective cohort of GBS-positive, penicillin-allergic women with singleton…
Objectives Preterm premature rupture of membranes is associated with intra-amniotic infection and inflammation, and the impact of exposure to bacterial pathogens on gestational membranes is poorly understood. Our objective was…
Objectives Screening for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) in men who have sex with men (MSM) is based on risk and includes testing of extragenital sites. Despite the…
Objectives VT-1161 is a novel oral selective inhibitor of fungal CYP51 and is highly potent against Candida species. Vulvovaginal candidiasis (VVC) is a common disorder with 75% of all women…
Objectives Many studies have described the healthy vaginal microbiome. However, the effect of HIV infection on the vaginal microbiome is less well-understood. HIV+ women are known to be at greater…
Objectives In women with signs and symptoms of PID, the detection of Gardnerella vaginalis and Atopobium vaginae in the endometrium is associated with histologic evidence of endometritis. The aim of…
Objectives To analyze the cervical microbiota in women with preterm prelabor rupture of membranes (PPROM) by pyrosequencing and to document associations between cervical microbiota, cervical inflammatory response, microbial invasion of…
Objectives To determine if HIV positive pregnant women who receive both sulfadoxine-pyrimethamine (SP) for malaria prophylaxis and Highly Active Antiretroviral Therapy (HAART) have a different risk of having a low…
Objectives To estimate the association between antimicrobial peptide, cytokine, and chemokine concentrations in cervicovaginal secretions and in vitro HIV infectivity among pregnant and non-pregnant women. Methods Longitudinal prospective cohort study…
Objectives To determine whether specific features of placental pathology correlate with fetal injury, the fetal inflammatory response syndrome (FIRS) and/or fetal and amniotic fluid cytokine levels during experimental infection-induced preterm…
