Objective Noninvasive prenatal testing (NIPT), based on isolation of cell-free fetal DNA from maternal blood, is a highly efficient screening test for trisomies 21, 18, and 13. Guidelines recommend reserving…
The review by Walfisch et al alongside many other reviews draws out the debate on the peritoneal closure/nonclosure during cesarean delivery. Any discussion on pathophysiologic adhesion-formation most importantly should include that…
In an earlier publication by the Prospective Observational Trial to Optimize Pediatric Health in Intrauterine Growth Restriction (PORTO) study group, the definition of fetal growth restriction (FGR) in fetuses that…
The minimally invasive approach for hysterectomy with proven benefits and lower morbidity has become the gold standard, even in women with large uterine masses. Most women with a malignant condition…
Objective We sought to compare the predictive power of published modified obstetric early warning scoring systems (MOEWS) for the development of severe sepsis in women with chorioamnionitis. Study Design This…
Materials and Methods Participants and recruitment Nulliparous women with singleton pregnancies were recruited from hospitals affiliated with 8 clinical centers: Case Western University; Columbia University; Indiana University; University of Pittsburgh;…
Objective Autism spectrum disorder (ASD) is associated with preterm birth (PTB), although the reason underlying this relationship is still unclear. Our objective was to examine DNA methylation patterns of 4…
Objective Mitochondrial DNA (mtDNA) encodes the proteins of the electron transfer chain to produce adenosine triphosphate through oxidative phosphorylation, and is essential to sustain life. mtDNA is unique from the…
Materials and Methods We compiled available literature including all studies reporting long-term (longer than 1 year) neurological outcome after common fetal interventions from 1990 through 2014. Institutional review board approval…
Objective While pregnancy-related severe liver disorders are rare, when they occur morbidity and mortality rates are increased for mothers and infants. The objective of this study was to examine the…
