There is a substantial body of literature that links psychological stress to adverse pregnancy outcomes, particularly preterm birth. Comparatively few studies have examined potential biologic mechanisms that explain these associations….
Objective The objective of the study was to identify metabolomic markers in maternal first-trimester serum for the detection of fetal congenital heart defects (CHDs). Study Design Mass spectrometry (direct injection/liquid…
Objective The objective of the study was to evaluate the association between gestational weight gain, per the 2009 Institute of Medicine (IOM) recommendations, and offspring overweight/obesity at 2-5 years of…
Objective The objective of the study was to combine early, direct assessment of the placenta with indirect markers of placental development to identify pregnancies at greatest risk of delivering small-for-gestational…
Materials and Methods Participants Participants who had a normotensive pregnancy formed the control group in follow-up studies assessing cerebral long-term consequences of preeclampsia. Recruitment and selection criteria have been published…
Objective We sought to measure the prevalence of illicit drug use in our obstetric population, to identify the drugs being used, and to determine whether a modified version of the…
Objective Because obesity is a risk factor for placental dysfunction, we hypothesized that maternal body mass index (BMI) would be associated with alterations in serum angiogenic markers. Study Design We…
Materials and Methods Study population We selected our study cohort from the database of the Consortium on Safe Labor, a study conducted by the Eunice Kennedy Shriver National Institute of…
Objective The purpose of this study was to evaluate the relationship between gestational age (GA) and induction of labor (IOL) and the rate of cesarean delivery in women with mild…
Objective We determined the potential programming effects of maternal obesity and high-fat (HF) diet during pregnancy and/or lactation on offspring metabolic syndrome. Study Design A rat model of maternal obesity…
