GYNECOLOGY

Maternal obesity during pregnancy leads to derangements in one-carbon metabolism and the gut microbiota: implications for fetal development and offspring wellbeing

Aug 28, 2022 by in GYNECOLOGY Comments Off on Maternal obesity during pregnancy leads to derangements in one-carbon metabolism and the gut microbiota: implications for fetal development and offspring wellbeing

A healthy diet before and during pregnancy is beneficial in acquiring essential B vitamins involved in 1-carbon metabolism, and in maintaining a healthy gut microbiota. Each play important roles in…

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Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis

Apr 16, 2022 by in GYNECOLOGY Comments Off on Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis

Background Bacterial vaginosis—a condition defined by a shift from Lactobacillus dominance to a polymicrobial, anaerobic bacterial community—increases the risk of acquiring sexually transmitted infections and other complications of the female…

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The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Apr 16, 2022 by in GYNECOLOGY Comments Off on The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Background Progesterone, acting via its nuclear receptors called progesterone receptors, promotes myometrial relaxation during pregnancy, and suspension of this activity triggers labor. We previously found that 20α-hydroxysteroid dehydrogenase causes a…

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Newborns’ passive humoral SARS-CoV-2 immunity following heterologous vaccination of the mother during pregnancy

Apr 16, 2022 by in GYNECOLOGY Comments Off on Newborns’ passive humoral SARS-CoV-2 immunity following heterologous vaccination of the mother during pregnancy

Objective Vaccination in the SARS-CoV-2 pandemic is important, especially to protect pregnant women and the unborn. In 2021, the messenger RNA (mRNA)-based vaccines BNT162b2 (BioNTech/Pfizer) and mRNA-1273 (Moderna), and the…

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