Reproductive endocrinology: Neuroendocrinology, Gonadotropins, Sex Steroids, Prostaglandins, Ovulation, Menstruation, and Hormone Assay

Aug 8, 2021 by in GYNECOLOGY Comments Off on Reproductive endocrinology: Neuroendocrinology, Gonadotropins, Sex Steroids, Prostaglandins, Ovulation, Menstruation, and Hormone Assay

Key points • Gonadotropin-releasing hormone (GnRH) analogs are synthesized by substitution of amino acids in the parent molecule at the 6 and 10 positions for GnRH agonists and at the…

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Medical-legal risk management

Aug 8, 2021 by in GYNECOLOGY Comments Off on Medical-legal risk management

Key points • Malpractice is patient injury secondary to failure to exercise that degree of care used by reasonably careful physician of like qualifications • Negligence is failure to extend…

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Evidence-based medicine and clinical epidemiology

Aug 8, 2021 by in GYNECOLOGY Comments Off on Evidence-based medicine and clinical epidemiology

Key points • Evidence-based medicine (EBM) seeks to improve the care of patients and the delivery of care to patients. • Descriptive-observational studies, including cross-sectional studies and case series, help…

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Fertilization and embryogenesis

Aug 8, 2021 by in GYNECOLOGY Comments Off on Fertilization and embryogenesis

Key points • Oocyte meiosis is arrested in prophase I from the fetal period until a luteinizing surge (LH) preceding ovulation. With the LH surge, the oocyte completes meiosis I…

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Reproductive genetics

Aug 8, 2021 by in GYNECOLOGY Comments Off on Reproductive genetics

Key points • Virtually all human diseases have an underlying genetic component. All health care professionals need a basic level of familiarity with genetics and genomics because it is an…

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Section 5 – Malformations

Aug 7, 2021 by in PEDIATRICS Comments Off on Section 5 – Malformations

Section 5 Malformations Neural Tube Defects and Patterning Defects Chapter 37 Defects of Neural Tube Closure and Axial Mesodermal Defects Marc Del Bigio One of the critical early steps in…

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Section 7 – Spinal and Neuromuscular Disorders

Aug 7, 2021 by in PEDIATRICS Comments Off on Section 7 – Spinal and Neuromuscular Disorders

Section 7 Spinal and Neuromuscular Disorders Arthrogryposis Chapter 49 Arthrogryposis Multiplex Congenita Mirna Lechpammer Definition, Epidemiology, and Genetics Arthrogryposis multiplex congenita (AMC), or arthrogryposis, and multiple congenital contractures (MCC) are…

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