Treatment Modalities for Fibroids, Indications, Risks, and Benefits

Feb 26, 2018 by in GYNECOLOGY Comments Off on Treatment Modalities for Fibroids, Indications, Risks, and Benefits

© Springer International Publishing AG 2018Nash S. Moawad (ed.)Uterine Fibroidshttps://doi.org/10.1007/978-3-319-58780-6_3 3. Treatment Modalities for Fibroids, Indications, Risks, and Benefits Deepika Garg1   and James H. Segars2   (1) Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY 11219, USA…

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Sperm Freezing Injuries

Feb 26, 2018 by in GYNECOLOGY Comments Off on Sperm Freezing Injuries

Fig. 15.1 Mechanism of DNA injury during cryopreservation Apoptosis markers (caspase activation, DNA damage and phosphatidylserine externalisation) have been linked to male infertility in numerous studies. Spermatozoa positive for active…

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Risk Preparedness in Sperm Banks

Feb 26, 2018 by in GYNECOLOGY Comments Off on Risk Preparedness in Sperm Banks

Fig. 16.1 The overall risk analysis/management framework This simplified diagrammatic overview of risk analysis may seem somewhat facile in relation to an apparently simple process such as sperm banking where…

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Etiology of Cancer-Induced Male Infertility

Feb 26, 2018 by in GYNECOLOGY Comments Off on Etiology of Cancer-Induced Male Infertility

Fig. 1.1 The hypothalamic-pituitary-gonadal axis. The hypothalamus signals the anterior pituitary to release LH and FSH to, respectively, stimulate testosterone production and spermatogenesis in the testicles. This system is regulated…

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Germ Cell Transplantation and Neospermatogenesis

Feb 26, 2018 by in GYNECOLOGY Comments Off on Germ Cell Transplantation and Neospermatogenesis

Fig. 20.1 Germ cell transplantation. Germ cells obtained from a donor testis are transplanted into the recipient testis either directly or after propagation in vitro. To improve donor cell colonization…

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Fertility Preservation in Hypogonadal Men

Feb 26, 2018 by in GYNECOLOGY Comments Off on Fertility Preservation in Hypogonadal Men

Medication Administration Dosage/frequency Special considerations Selective estrogen receptor modulators (SERM) Oral Clomiphene citrate 25–50 mg daily, tamoxifen 20 mg daily Generally well tolerated. Off-label use for male infertility. More potent…

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