Disorders of Ketogenesis Stephen I. Goodman Hepatic biosynthesis of ketone bodies involves the condensation of acetyl-CoA and acetoacetyl-CoA to hydroxymethylglutaryl-CoA (HMG-CoA) by HMG-CoA synthetase, followed by hydrolysis of…
Resiliency in Children and Adolescents Saul Levine Resiliency is the ability to rebound from real, experienced adversity. It refers to an individual’s use of inner strengths and outer…
Chronic Fatigue Syndrome David S. Leslie Generalized fatigue is a frequent complaint during many common pediatric infectious illnesses. Additionally, chronic diseases of childhood often are characterized by associated…
Undue Susceptibility to Infection Talal A. Chatila Each year, a large number of children are evaluated by their primary care physicians for recurrent infections, an especially common event…
Scrotal Masses David J. Breland and Mark L. Rubinstein TESTICULAR TORSION Testicular torsion is a surgical emergency, and clinicians caring for adolescent males must have a high index…
Gay and Lesbian Parents Cindy M. Schorzman and Melanie A. Gold BACKGROUND Same-gender couples live in almost every county in the United States, and nearly 25% are raising…
Stabilization and Transport Deborah Lerner, George E. Lister, and Julio Pérez Fontán Complex, high-acuity services cannot be offered at every site where children receive medical care. These services…
Management of Cerebral Edema and Elevated Intracranial Pressure Steven G. Kernie Most forms of acute head injury increase the volume of the intracranial contents. Cerebral edema, hemorrhage, acute…
Bacteremia, Sepsis, and Septic Shock Stephanie H. Stovall and Richard F. Jacobs Children presenting with pathogenic bacteria in a blood culture (bacteremia) manifest a wide spectrum of clinical…
Neuromuscular Disorders Lori A. Karol INTRODUCTION Many neuromuscular disorders are dealt with in some detail throughout this text, and this chapter focuses on those that commonly require orthopedic…
