Figure 26.1 The difference between a wide and narrow therapeutic window Pregnancy and pharmacokinetics Due to the very large physiological changes associated with pregnancy, it is mainly drug handling that…
Figure 16.1 Blood supply to, and venous drainage from, the hypothalamo–pituitary axis Histology of the hypothalamo-pituitary region There are three types of hypothalamic neurosecretory cells. Magnocellular neurons secrete arginine vasopressin…
Figure 29.1 The main stages of follicle growth Figure 29.2 Cross-section through an antral, or Graafian, follicle Selection of a single follicle and oocyte Folliculogenesis is defined as growth of…
Figure 13.1 Sagittal sections showing the cephalocaudal folding of the embryo and the formation of the primitive gut Table 13.1 Derivatives of the primitive gut Pharyngeal gut Pharynx and related…
Likelihood ratio or Odds ratioProbability/(1 – probability)Accuracy(TP + TN)/total T = true | F = false | P = positive | N = negative Sensitivity Sensitivity is the proportion of…
Figure 30.1 Anatomy of the male reproductive tract and fine structure of the rete, epididymis and vas deferens The internal structure of the testes The testes are oval structures of…
Table 8.3 Organs that regulate calcium homeostasis Organ Function Kidney Response to Ca2+, PTH, vitamin D and calcitonin Activation of vitamin D Regulation of Ca2+ and PO43− reabsorption and excretion…
Figure 15.1 Development of the conceptus from the eight-cell stage to the time of implantation In the preimplantation phase, new trophoblast develops from the base of the inner cell mass…
Figure 17.1 Hypothalamo–pituitary–adrenal axis and control of cortisol secretion Cells in the paraventricular nucleus of the hypothalamus secrete corticotrophin-releasing hormone (CRH). Released from nerve terminals in the median eminence, this…
Figure 23.1 Mechanisms of increased vascular permeability Chemical mediators Broadly speaking, the chemical mediators of inflammation originate either from plasma or from cells (Table 23.3). The production of active chemical…
