Enoxaparin for the prevention of preeclampsia and intrauterine growth restriction in women with a history: a randomized trial

Apr 24, 2017 by in GYNECOLOGY Comments Off on Enoxaparin for the prevention of preeclampsia and intrauterine growth restriction in women with a history: a randomized trial

Background Preeclampsia and small-for-gestational-age pregnancy are major causes of maternal and perinatal morbidity and mortality. Women with a previous pregnancy affected by these conditions are at an increased risk of…

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Differences in placental telomere length suggest a link between racial disparities in birth outcomes and cellular aging

Apr 24, 2017 by in GYNECOLOGY Comments Off on Differences in placental telomere length suggest a link between racial disparities in birth outcomes and cellular aging

Background Health disparities begin early in life and persist across the life course. Despite current efforts, black women exhibit greater risk for pregnancy complications and negative perinatal outcomes compared with…

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Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta

Apr 24, 2017 by in GYNECOLOGY Comments Off on Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta

Background Failure of physiologic transformation of spiral arteries has been reported in preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact or ruptured membranes. Spiral arteries with…

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The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes

Apr 24, 2017 by in GYNECOLOGY Comments Off on The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes

Background Intrauterine balloon tamponade is an effective treatment for postpartum hemorrhage when first-line treatments fail. The optimal duration of intrauterine balloon tamponade for management of postpartum hemorrhage is unclear. Objective…

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Infant outcomes among women with Zika virus infection during pregnancy: results of a large prenatal Zika screening program

Apr 24, 2017 by in GYNECOLOGY Comments Off on Infant outcomes among women with Zika virus infection during pregnancy: results of a large prenatal Zika screening program

Background Zika virus infection during pregnancy is a known cause of congenital microcephaly and other neurologic morbidities. Objective We present the results of a large-scale prenatal screening program in place…

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Gestational hypertension is associated with increased risk of type 2 diabetes in adult offspring: the Helsinki Birth Cohort Study

Apr 24, 2017 by in GYNECOLOGY Comments Off on Gestational hypertension is associated with increased risk of type 2 diabetes in adult offspring: the Helsinki Birth Cohort Study

Background Women with hypertensive disorders in pregnancy are at an increased risk of cardiovascular disease and type 2 diabetes later in life. Offspring born from these hypertensive pregnancies have increased…

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Pelvic floor morphometry and function in women with and without puborectalis avulsion in the early postpartum period

Apr 24, 2017 by in GYNECOLOGY Comments Off on Pelvic floor morphometry and function in women with and without puborectalis avulsion in the early postpartum period

Background Pelvic floor muscles are subject to considerable stretching during vaginal birth. In 13-36% of women, stretching results in avulsion injury whereby the puborectalis muscle disconnects from its insertion points…

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