Neonatal Cholestasis
Neonatal Cholestasis Donald A. Novak Frederick J. Suchy William F. Balistreri Neonatal cholestasis, defined as prolonged conjugated hyperbilirubinemia, is the end result of impaired bile flow and excretion. The cumulative…
Developmental Disorders of Gastrointestinal Function
Developmental Disorders of Gastrointestinal Function Colston F. McEvoy Most gastrointestinal disease that presents in the neonatal period can be attributed to congenital anomalies. These defects in gut structure or function…
Cardiovascular Disease in the Newborn
Cardiovascular Disease in the Newborn Anne Marie Valente Craig E. Fleishman Norman S. Talner The clinical approach to cardiovascular problems of the newborn must take into account the structural and…
Cardiovascular Surgery in the Newborn
Cardiovascular Surgery in the Newborn Gary S. Kopf Dennis M. Mello Congenital heart disease (CHD) occurs in 0.8% to 0.9% of live births. Approximately 30% of these patients will need…
Cardiovascular Embryology
Cardiovascular Embryology Louis I. Bezold The development of the cardiovascular system—first organ system to reach functional maturity—is essentially complete by 8 weeks’ gestational age in humans. The critical period of…
Epidemiology of Congenital Heart Disease
Epidemiology of Congenital Heart Disease David E. Fixler Congenital heart disease (CHD) is a leading cause of death during the first year of life. Malformations of the heart occur in…
Bronchopulmonary Dysplasia
Bronchopulmonary Dysplasia Kathleen A. Kennedy Joseph B. Warshaw Most neonates with acute lung disease recover completely within the first week of life. Some of these infants, however, develop chronic respiratory…
Persistent Pulmonary Hypertension
Persistent Pulmonary Hypertension Gross Ian PATHOGENESIS During fetal life the tone in the pulmonary arterial system is increased and the pressure on the right side of the heart is greater…
Meconium Aspiration Syndrome
Meconium Aspiration Syndrome Gross Ian Meconium is passed into the amniotic fluid in approximately 10% of all births. Although passage of meconium may be associated with intrauterine fetal hypoxia, it…
