Hematopoiesis and Hematologic Diseases Charles T. Quinn George R. Buchanan Hematologic problems are encountered daily by pediatricians caring for sick newborn infants. Alterations in the hematopoietic system most often are…
Urinary Tract Infections Marc H. Lebel EPIDEMIOLOGY The incidence of bacteriuria in the neonate is low, ranging from 0.1% to 1.9% in full-term infants and up to 10% in low-birth-weight…
Mineral Metabolism in the Newborn Joseph M. Gertner SKELETAL DEVELOPMENT IN THE FETUS AND NEONATE Histogenesis and Organogenesis of the Skeleton At the end of a 40-week term of gestation,…
Infant of the Diabetic Mother Joseph B. Warshaw William W. Hay Jr. INTRODUCTION AND DEFINITIONS Diabetes mellitus is the most common medical complication of pregnancy. Diabetes occurs in two forms…
Neonatal Endocrinology Elizabeth A. Catlin Mary M. Lee The transition from an intrauterine to an extrauterine environment at birth requires neonates to make rapid and appropriate homeostatic adaptations for independent…
Renal and Genitourinary Diseases Billy S. Arant Jr. In most newborns, the kidneys are able to maintain body fluid homeostasis within certain limits. However, these organs may be inadequate to…
Short Bowel Syndrome Jon A. Vanderhoof PATHOPHYSIOLOGY In pediatrics, short bowel syndrome is perhaps the most common indication for the chronic use of parenteral nutrition. In the neonatal period, massive…
Necrotizing Enterocolitis Kathleen J. Motil Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in the infant. This disorder encompasses several distinct disease entities that differ from the most common…
Distended Abdomen John H. Seashore Newborn infants normally have protuberant abdomens owing to the relatively large size of their viscera, so judging distention may be more challenging than in older…
Sucking and Swallowing Disorders and Gastroesophageal Reflux Colston F. McEvoy Sucking and swallowing begin prenatally, with pharyngeal swallowing observed as early as 10 to 11 weeks’ gestation and suckling seen…
