. Glomerular Diseases
Glomerular Diseases Allison A. Eddy Glomerular diseases present clinically in several different ways, depending on the nature and severity of the primary disease and the extent to which…
. Diabetes Mellitus
Diabetes Mellitus Arlan L. Rosenbloom CLASSIFICATION AND DIAGNOSIS The diagnosis of diabetes includes a wide variety of diseases characterized by hyperglycemia. Because insulin is the only physiologically important…
. Disorders of Digestion and Absorption
Disorders of Digestion and Absorption Ivor D. Hill and Ricardo A. Caicedo EVALUATION OF THE CHILD WITH MALABSORPTION The assimilation of ingested nutrients involves a complex integrated process…
. Arrhythmias
Arrhythmias George F. Van Hare GENERAL PRINCIPLES ANATOMY AND PHYSIOLOGY The heart has specialized cells collected into nodes and tracts. The sinoatrial node, near the junction of the…
. Metabolic Abnormalities
Metabolic Abnormalities William W. Hay Jr. DISORDERS OF GLUCOSE METABOLISM Normal postnatal glucose homeostasis is established by increased glucose production and glucose utilization.1 Factors that promote glucose production…
. Disorders of Glycogen Metabolism
Disorders of Glycogen Metabolism Priya S. Kishnani and Yuan-Tsong Chen GLYCOGEN STORAGE DISEASE Glycogen, the storage form of glucose in animal cells, is composed of glucose residues joined…
. Anemia Due to Diminished Red Blood Cell Production
Anemia Due to Diminished Red Blood Cell Production Zora R. Rogers Anemia may be the first recognized hematologic finding in a child whose bone marrow is not functioning…
. Hemoglobinopathies
Hemoglobinopathies Charles T. Quinn Hemoglobin (Hb) is the oxygen-carrying protein within red blood cells (RBCs). It is composed of four globular protein subunits, called globins, and four oxygen-binding…
. Mucopolysaccharidosis, Glycoproteinosis, and Mucolipidosis
Mucopolysaccharidosis, Glycoproteinosis, and Mucolipidosis James Edmond Wraith MUCOPOLYSACCHARIDOSIS The mucopolysaccharidoses (MPS) are a family of disorders that are caused by inherited defects in the catabolism of sulfated components…
. Disorders of Granulocytes
Disorders of Granulocytes R. Alexander Blackwood and Lawrence A. Boxer White blood cells, or leukocytes, are part of the innate immune system. They are one of the body’s…
