Introduction Polycystic ovary syndrome (PCOS) is a highly prevalent (5%–10%) endocrine-metabolic dysfunction in adult women, characterized by chronic oligo-anovulation, hyperandrogenism, and polycystic ovarian morphology (PCOM). Most women with PCOS also…
Introduction (why to use antiandrogens) Excessive androgen secretion, manifested as hirsutism, acne, and/or alopecia, constitutes one of the cardinal features in women and adolescents with polycystic ovary syndrome (PCOS) ….
Vitamin D metabolism Vitamin D is a steroid hormone, synthesized mainly by the skin on exposure to natural sunlight, with < 10%–20% deriving from the diet . Vitamin D is…
Introduction Polycystic ovary syndrome (PCOS) is the most common endocrinopathy, affecting women in reproductive age. The manifestations of this condition consist of ovulatory, metabolic, aesthetic, psychological, and possibly an elevated…
Overview of metabolic risk profile and complications of NAFLD Excessive hepatic fat accumulation defines the primary event in the continuum of nonalcoholic fatty liver disease (NAFLD) that has become the…
Introduction Polycystic ovary syndrome (PCOS) is associated with neuroendocrine dysfunctions, insulin resistance (IR), impaired ovarian steroidogenesis and hyperandrogenism . Although the etiology of PCOS is still poorly known, androgens and…
Introduction The myth of Ariadne’s thread is a fitting analogy for providing a practical and logical algorithm for the management of anovulatory PCOS. The legend tells of King Minos who,…
Introduction Polycystic ovary syndrome (PCOS), a multifactorial disorder, involves mainly reproductive but also other endocrine systems. Based on the current Rotterdam criteria, the prevalence of PCOS varies between 5% and…
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-aged women characterized by clinical or biochemical hyperandrogenism, oligo-anovulation, and polycystic ovarian morphology. Women with PCOS have increased risk…
Funding sources This work was supported by the Brazilian National Institute of Hormones and Women’s Health/Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq INCT grant number 465482/2014-7) and Fundação de…
