Selecting the appropriate dosage form and route of administration is a crucial, but underappreciated, component in the successful treatment of children with epilepsy. For example, some children…
INTRODUCTION The possible occurrence of myoclonic epilepsy in children with nonprogressive encephalopathy has been reported in the literature for many years by various authors (1–5). However, in…
INTRODUCTION There are several forms of dietary treatment for epilepsy; arguably, the most important and effective is the ketogenic diet (KD). It is a high-fat, low-carbohydrate, and…
As advocated by physicians and patient activist groups, the treatment goal for patients with epilepsy is to eliminate both seizures and adverse side effects of treatment (1)….
Experimental studies in diverse preparations, including brain slices and whole animals, have led to the view that the generation of focal epileptic activity represents an imbalance between…
INTRODUCTION The subgroup of generalized epilepsies which previously was known as idiopathic is now suggested to be termed genetic (1). These changes are part of those proposed…
Zonisamide (ZNS) was first synthesized by Dainippon Pharmaceutical Company in Osaka, Japan, in 1974 (1). ZNS was originally developed in an effort to discover medications for psychiatric…
The progressive myoclonic epilepsies (PME) represent a genetically heterogeneous group of epilepsies that associate, as a hallmark, cortical myoclonus, other types of epileptic seizures, and a progressive…
Seizures are time-limited paroxysmal events that result from abnormal, involuntary rhythmic activity affecting small or large neuronal networks in the brain (1,2). The term seizure appears to…
OCCIPITAL EPILEPSY OF GASTAUT Late-onset childhood occipital epilepsy (Gastaut type) in its pure form is a self-limited epilepsy, presenting with focal seizures of childhood or adolescence. It…
