HIV Infection
HIV Infection Avinash K. Shetty and Yvonne A. Maldonado INTRODUCTION Perinatal transmission is the most common route of human immunodeficiency virus type 1 (HIV-1) infection among infants and children.1 Since…
Thymic Aplasia and T-Cell Disorder
Thymic Aplasia and T-Cell Disorder Yu-Lung Lau and Pamela Lee INTRODUCTION As detailed in chapter 49, host defense mechanisms against pathogens are defective in the newborn as a result of…
Initial Management of Metabolic Acidosis
Initial Management of Metabolic Acidosis Kristina Cusmano-Ozog and Kimberly Chapman DIAGNOSIS/INDICATION Metabolic acidosis in the neonate can have several causes, including increased acid intake from an exogenous source, increased endogenous…