Abstract Male infertility affects men worldwide with about 20 percent of couples having male factor infertility [1]. The routine semen analysis is the first step in the assessment of male…
Abstract Fertility, pregnancy and childbirth are connected and inseparable realities that ultimately need to combine to result in a “baby at home”; each one of these phenomena possesses their own…
Abstract Spermatozoa are mature male gametes that are produced in the testes of a healthy man by spermatogenesis, with further maturation of sperm taking place during their transit through the…
Abstract Infertility is a major public health concern affecting up to 25 percent of couples worldwide [1]. It is defined by the failure of a couple to achieve conception after…
Abstract Several sperm DNA integrity and chromatin quality assays have been developed and used for the detection of sperm DNA fragmentation and chromosomal aberrations [1, 2]. The Comet assay is…
Abstract The year 2020 is the fortieth anniversary of the introduction of the concept of “sperm DNA fragmentation” as related to human and animal male factor fertility. This concept was…
Abstract Sperm are highly specialized cells, evolved to function as vehicles for the transport of the paternal genome to the oocyte. The sperm cell is characterized by a distinct head,…
Abstract Gametogenesis is a central biological process for sexual reproduction. In this process, both haploid male and female gametes are needed for successful fertilization. Male gamete or sperm are produced…
Abstract In order to transport an intact and complete paternal genome to the oocyte, spermatozoa are characterized by an extremely compacted nuclear DNA as compared to the nucleus of somatic…
Abstract Oxidative stress (OS) is the consequence of an imbalance between reactive oxygen species (ROS) and the failure of antioxidants to neutralize excessive ROS production. Although many sperm functions require…
