Abstract The regulation of the endocrine and reproductive function of the testis is under the concerted action of gonadotropin-releasing hormone (GnRH) and gonadotropins, such as luteinizing hormone (LH) and follicle-stimulating…
Abstract The primary aim of this chapter is to provide practical, evidence-based information pertinent to the specific detection of anti-sperm antibodies (ASA) in males and females and the assessment of…
Abstract This chapter provides detailed practical information about testing for sperm antibodies and interpretation of the results of various antibody tests. It also briefly reviews our knowledge about anti-sperm antibodies…
Abstract This chapter considers the effect of paternal age on semen analysis, sperm function and DNA damage, as well as age-related impact on male fertility, both natural conception (time to…
Abstract The sperm epigenome is unique and of profound clinical importance based on its role in influencing embryogenesis. Potentially, the sperm epigenome can also be of importance to the clinician…
Abstract Male infertility is a highly heterogeneous, multifactorial, complex pathology of the reproductive system, affecting approximately 7% of the general male population. Genetic factors are estimated to contribute to nearly…
Abstract Male infertility is a common condition estimated to be a contributory factor in as many as 50% of couples experiencing problems with conception. It is also a key catalyst…
Abstract This chapter describes techniques for the preparation of human spermatozoa for assisted conception. Traditional swim-up techniques depend on the intrinsic motility of human spermatozoa and have been used as…
