Chapter 10 – Breast Cancer Therapy and Fertility
Abstract Breast cancer is the most common cancer disease in women worldwide, being also the third most common incident cancer overall, with a global estimated of 1.7 million new diagnosed…
Chapter 11 – Fertility Preservation in Young Adults with Gastrointestinal and Hematological Malignancies
Abstract Cancer is one of the most important public health problems all around the world. It is the second leading cause of death globally. Thousands of young women are diagnosed…
Chapter 8 – Fertility Preservation in Women with Ovarian Endometriomas
Abstract Endometriosis is a benign estrogen-dependent gynecological disease, known to occur in 7–10% of women of childbearing age [1, 2]. This percentage may rise to 30–50% if only women presenting…
Chapter 6 – Principles of Vitrification as a Method of Cryopreservation in Reproductive Biology and Medicine
Abstract The popularity of vitrification (literally, glass formation) as a method of cryopreservation for reproductive cells, tissues, and even organs is evident from the rising number of citations of these…
Chapter 7 – Fertility Preservation in Non-Cancer Patients
Abstract The increasing survival rates of cancer patients [1] have encouraged many specialists to focus on the irreversible consequences of chemotherapy and radiotherapy. Chemotherapy and radiotherapy treatment for cancer or…
Chapter 5 – Life and Death in the Germ Line
Abstract Apoptosis, a physiological process for the controlled deletion of cells, is critical for the regulation of cell numbers, the management of morphogenesis during embryonic development, and the orchestration of…
Chapter 4 – The Need for Fertility Preservation in Cancer Patients
Abstract The rapid expansion in reproductive medicine services in recent decades, with notable technological advances in oocyte cryopreservation [1] and artificial reproductive techniques using mature gametes [2], has aligned with…
Chapter 3 – The Effect of Radiotherapy on the Human Reproductive System
Abstract Cancer in childhood is rare. The most recent SEER Cancer Statistics Review, released in April 2018 and covering 2011–2015, shows that for ages 0–14 the incidence of all cancer…
Chapter 1 – The Evolution of the Assisted Reproduction Technologies
Abstract It could be said that the first instance of assisted reproductive technology (ART) was when an eminent surgeon, John Hunter (1728–1793) of London (Figure 1.1), assisted a woman in…
Chapter 2 – The Effect of Chemotherapy on the Human Reproductive System
Abstract Chemotherapy induces ovarian damage in a drug- and dose-dependent manner, and is related to age at the time of treatment, with progressively smaller doses required to produce ovarian failure…
