Abstract Endocervical glandular neoplasms comprise a plethora of challenging cytologic patterns and a dichotomy of human papilloma virus (HPV)-positive and HPV-negative tumors. New developments in the HPV-positive neoplasms center on…
Abstract This chapter addresses a spectrum of neoplasms that can be found in the vagina, ranging from the more common, the squamous intraepithelial lesions, to the more obscure. Particularly problematic…
Abstract Vulvovaginal mesenchymal neoplasms and non-neoplastic proliferations are rare. Nonetheless, the spectrum of lesions is wide. A major subset includes tumors preferentially seen in this anatomic location (vulvovaginal stromal tumors)….
Abstract Vulvar squamous neoplasia clinical management depends on the identification of low-grade squamous intraepithelial lesions (exophytic and flat condyloma), high-grade squamous intraepithelial lesions (classic and differentiated vulvar intraepithelial neoplasias [VINs]),…
Abstract The histologic zones of the anal canal include the colorectal zone, anal transitional zone (ATZ), non–hair-bearing squamous mucosa, and perianal skin. The dentate line is the distal end of…
Abstract This chapter addresses a number of nonneoplasitc conditions. They are important mimics of neoplasia, challenges in management, or rare entities that might cause diagnostic confusion. For example, a prolapsed…
Abstract Pigmented lesions of the vulva are a concern to patients, their health care providers, and pathologists. Gynecologists are particularly wary of pigmented lesions of the vulva because the prognosis…
Abstract Infections of the female genital tract are a significant cause of morbidity. Many infections are sexually transmitted, including trichomoniasis, gonorrhea, chancroid, granuloma inguinale, lymphogranuloma venereum, syphilis, chlamydia, herpes, and…
Abstract Glandular neoplasms of the vulvar are uncommon, and this chapter focuses on those entities that are particularly relevant with emphasis on confusing areas and potential pitfalls. Critical issues when…
Abstract Virtually any inflammatory disorder of skin can involve the vulva and the wide spectrum of inflammatory disorders having varied appearances at different stages makes classification extremely challenging. Furthermore, clinical…
