Congenital Toxoplasmosis
Congenital Toxoplasmosis Galit Holzmann-Pazgal KEY POINTS Toxoplasmosis can be acquired without exposure to cats via ingestion of infected oocysts in contaminated food or water or tissue cysts in undercooked/raw meat….
Bacterial and Fungal Infections
Bacterial and Fungal Infections Karen M. Puopolo KEY POINTS Risk factors for neonatal early-onset sepsis (EOS) include prematurity, documented maternal colonization with group B Streptococcus (GBS), intrapartum fever and other…
Viral Infections
Viral Infections Sallie R. Permar KEY POINTS Vertically transmitted (mother to child) viral infections of the fetus and newborn can generally be divided into three distinct categories by transmission modes—congenital,…
Thrombocytopenia
Thrombocytopenia Emöke Deschmann Matthew Saxonhouse Martha Sola-Visner KEY POINTS The most common cause of mild-to-moderate, early-onset thrombocytopenia in well-appearing neonates is placental insufficiency, frequently manifesting as small for gestational status…
Polycythemia
Polycythemia Deirdre O’Reilly KEY POINTS Polycythemia and hyperviscosity of the blood in newborns may lead to symptoms such as hypoglycemia, poor feeding, and irritability; yet, most newborns with polycythemia are…
Neonatal Thrombosis
Neonatal Thrombosis Katherine A. Sparger Munish Gupta KEY POINTS Neonatal thrombosis is a rare but significant cause of neonatal morbidity and mortality. The presence of an intravascular catheter is the…
Blood Products Used in the Newborn
Blood Products Used in the Newborn Steven R. Sloan KEY POINTS Blood components should be transfused when clinically indicated to promote oxygen delivery and coagulation. Immunocompromised patients such as those…
Cardiac Disorders
Cardiac Disorders John P. Breinholt KEY POINTS The incidence of congenital heart disease is 0.6% to 0.8% of all live births. The most serious congenital heart lesions are usually symptomatic…
