Clinical Management

Sep 20, 2018 by in GYNECOLOGY Comments Off on Clinical Management

Keywords preeclampsia, eclampsia, hypertension, evidence-based management, magnesium sulfate therapy   Editors’ comment: Although not an obstetrician or a clinician, Leon Chesley, PhD, was associated through most of his career with…

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The Kidney in Normal Pregnancy and Preeclampsia

Sep 20, 2018 by in GYNECOLOGY Comments Off on The Kidney in Normal Pregnancy and Preeclampsia

Keywords glomerular filtration, renal blood flow, relaxin, proteinuria, podocyturia, renal vascular resistance, preeclampsia, glomerular endotheliosis, renal biopsy   Editors’ comment: The revision of this chapter includes the welcoming of a…

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Platelets, Coagulation, and the Liver

Sep 20, 2018 by in GYNECOLOGY Comments Off on Platelets, Coagulation, and the Liver

Keywords platelets, liver, coagulation, HELLP syndrome, hemolysis, thrombophilia   Editors’ comment: This chapter of the fourth edition of Chesley’s textbook has been updated. In order to do so, the editors…

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Chronic Hypertension and Pregnancy

Sep 20, 2018 by in GYNECOLOGY Comments Off on Chronic Hypertension and Pregnancy

Keywords pregnancy, superimposed preeclampsia, essential hypertension, pheochromocytoma, primary aldosteronism, renal artery stenosis, Cushing syndrome   Editors’ comments: The fourth edition adds two new authors to the chapter on chronic hypertension…

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The Renin-Angiotensin System, its Autoantibodies, and Body Fluid Volume in Preeclampsia

Sep 20, 2018 by in GYNECOLOGY Comments Off on The Renin-Angiotensin System, its Autoantibodies, and Body Fluid Volume in Preeclampsia

Keywords pregnancy, preeclampsia, total body water, intravascular volume, interstitial volume, renin–angiotensin–aldosterone system, natriuretic hormones, pressure natriuresis, Na + K + -ATPase, osmoregulation, vasopressin   Editors’ comment : The role of…

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Antihypertensive Treatment

Sep 20, 2018 by in GYNECOLOGY Comments Off on Antihypertensive Treatment

Keywords antihypertensive drugs, pregnancy, preeclampsia, systematic reviews   Editors’ comment: The authors in updating this chapter continue to emphasize the need for better study designs regarding the ideal antihypertensive drugs…

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Cardiovascular Alterations in Normal and Preeclamptic Pregnancy

Sep 20, 2018 by in GYNECOLOGY Comments Off on Cardiovascular Alterations in Normal and Preeclamptic Pregnancy

Keywords preeclampsia, cardiovascular system, systemic arterial circulation, hemodynamics, left ventricular mechanics, pregnancy response and later-life cardiovascular disease risk   Editors’ comment: The heart was a brief bystander in Chesley’s original…

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Prevention of Preeclampsia and Eclampsia

Sep 20, 2018 by in GYNECOLOGY Comments Off on Prevention of Preeclampsia and Eclampsia

Keywords Preeclampsia, eclampsia, prevention, low-dose aspirin, calcium supplementation, antioxidants, magnesium sulfate   Editors’ comment: The past two decades have seen many resources focused on the prevention of preeclampsia with minimal…

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Tests to Predict Preeclampsia

Sep 20, 2018 by in GYNECOLOGY Comments Off on Tests to Predict Preeclampsia

Keywords multivariable prediction models, proteomics, metabolomics, cell-free fetal DNA, podocyturia, angiogenic factors, uterine artery Doppler velocimetry   Editors’ comment: As noted by the authors in their Introduction, prediction tests had…

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