Hormones and pathogenesis of uterine fibroids

Nov 6, 2017 by in OBSTETRICS Comments Off on Hormones and pathogenesis of uterine fibroids

The role of ovarian steroid hormones in the pathogenesis of uterine fibroids is supported by epidemiological, clinical, and experimental evidence. Estradiol and progesterone induce mature leiomyoma cells to release mitogenic…

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The Epidemiology and Genetics of Uterine Leiomyoma

Nov 6, 2017 by in OBSTETRICS Comments Off on The Epidemiology and Genetics of Uterine Leiomyoma

Uterine leiomyomas (fibroids) are the most common benign neoplasms in premenopausal women, which confer significant morbidity during the reproductive years and represent a significant public health issue. The incidence of…

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