Vaginal microbicides to prevent human immunodeficiency virus infection in women: Perspectives on the female genital tract, sexual maturity and mucosal inflammation

Nov 9, 2017 by in OBSTETRICS Comments Off on Vaginal microbicides to prevent human immunodeficiency virus infection in women: Perspectives on the female genital tract, sexual maturity and mucosal inflammation

Topically applied vaginal microbicides to protect against human immunodeficiency (HIV) virus infection offer an important female-controlled prevention strategy. Microbicides have been in development for more than 2 decades, and have…

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Future strategies in microbicide development

Nov 9, 2017 by in OBSTETRICS Comments Off on Future strategies in microbicide development

The reduction in human immunodeficiency virus (HIV) infection in women demonstrated by pericoital use of tenofovir gel has encouraged the continued development of microbicides. Novel approaches include new ways to…

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Implementing microbicides in low-income countries

Nov 9, 2017 by in OBSTETRICS Comments Off on Implementing microbicides in low-income countries

The magnitude of the global human immunodeficiency virus (HIV) epidemic is determined by women from lower income countries, specifically sub-Saharan Africa. Microbicides offer women who are unable to negotiate safe…

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Contraception and pregnancy in microbicide trials

Nov 9, 2017 by in OBSTETRICS Comments Off on Contraception and pregnancy in microbicide trials

The distinctive feature of the human immunodeficiency virus (HIV) epidemic in Sub-Saharan Africa is the burden on women, in particular young women of reproductive age. Consequently, most late-phase effectiveness microbicide…

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