Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis

Apr 16, 2022 by in GYNECOLOGY Comments Off on Recurrent bacterial vaginosis following metronidazole treatment is associated with microbiota richness at diagnosis

Background Bacterial vaginosis—a condition defined by a shift from Lactobacillus dominance to a polymicrobial, anaerobic bacterial community—increases the risk of acquiring sexually transmitted infections and other complications of the female…

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The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Apr 16, 2022 by in GYNECOLOGY Comments Off on The selective progesterone receptor modulator-promegestone-delays term parturition and prevents systemic inflammation-mediated preterm birth in mice

Background Progesterone, acting via its nuclear receptors called progesterone receptors, promotes myometrial relaxation during pregnancy, and suspension of this activity triggers labor. We previously found that 20α-hydroxysteroid dehydrogenase causes a…

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Newborns’ passive humoral SARS-CoV-2 immunity following heterologous vaccination of the mother during pregnancy

Apr 16, 2022 by in GYNECOLOGY Comments Off on Newborns’ passive humoral SARS-CoV-2 immunity following heterologous vaccination of the mother during pregnancy

Objective Vaccination in the SARS-CoV-2 pandemic is important, especially to protect pregnant women and the unborn. In 2021, the messenger RNA (mRNA)-based vaccines BNT162b2 (BioNTech/Pfizer) and mRNA-1273 (Moderna), and the…

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Intrapartum ultrasound measurement of angle of progression at the onset of the second stage of labor for prediction of spontaneous vaginal delivery in term singleton pregnancies: a systematic review and meta-analysis

Apr 16, 2022 by in GYNECOLOGY Comments Off on Intrapartum ultrasound measurement of angle of progression at the onset of the second stage of labor for prediction of spontaneous vaginal delivery in term singleton pregnancies: a systematic review and meta-analysis

Objective This study aimed to investigate the diagnostic performance of transperineal ultrasound–measured angles of progression at the onset of the second stage of labor for the prediction of spontaneous vaginal…

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Failure of placental detachment in accreta placentation is associated with excessive fibrinoid deposition at the utero-placental interface

Apr 16, 2022 by in GYNECOLOGY Comments Off on Failure of placental detachment in accreta placentation is associated with excessive fibrinoid deposition at the utero-placental interface

Background The main histopathologic diagnostic criteria for the diagnosis of placenta accreta for more than 80 years has been the finding of a direct attachment of the villous tissue to…

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SARS-CoV-2 infection and subsequent changes in the menstrual cycle among participants in the Arizona CoVHORT study

Apr 16, 2022 by in GYNECOLOGY Comments Off on SARS-CoV-2 infection and subsequent changes in the menstrual cycle among participants in the Arizona CoVHORT study

Objective The menstrual cycle involves complex interactions between various tissues, hormones, and organ systems. As such, the menstrual cycle is sensitive to endogenous and exogenous factors, including infection and changes…

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