Objective Mitochondrial DNA (mtDNA) encodes the proteins of the electron transfer chain to produce adenosine triphosphate through oxidative phosphorylation, and is essential to sustain life. mtDNA is unique from the…
Materials and Methods We compiled available literature including all studies reporting long-term (longer than 1 year) neurological outcome after common fetal interventions from 1990 through 2014. Institutional review board approval…
Objective While pregnancy-related severe liver disorders are rare, when they occur morbidity and mortality rates are increased for mothers and infants. The objective of this study was to examine the…
Objective Screening for gestational diabetes mellitus commonly uses an oral glucose challenge test with a 50-g glucola beverage and subsequent venous puncture. However, up to 30% of pregnant women report…
Objective Cerebrovascular complications that are associated with hypertensive disorders of pregnancy (preeclampsia, chronic hypertension [CHTN], and gestational hypertension [GHTN]) are believed to be associated with impaired cerebral autoregulation, which is…
Materials and Methods The population-based case-control study providing the data for this report was designed to investigate factors associated with risk of CP, defined as a disorder of movement and/or…
Objective The purpose of this study was to compare the performance of first-trimester nuchal translucency (NT) cutoff of ≥3.5 mm with NT percentiles that were calculated for crown-rump length to…
Objective The purpose of this study was to provide an updated summary of the literature regarding the effects of tocolysis with indomethacin on neonatal outcome by systematically reviewing previously and…
Materials and Methods Cohort design, participant recruitment, and blood collection This nested case-control study originated from separate Canadian cohort studies of pregnant women recruited in Halifax, Nova Scotia, and in…
Objective Our objective was to examine the associations of total and trimester-specific gestational weight gain (GWG) rate with postpartum maternal weight and cardiometabolic risk. We hypothesized that first-trimester GWG would…
