Did drug therapy contribute?

May 23, 2017 by in GYNECOLOGY Comments Off on Did drug therapy contribute?

Case notes A healthy 68-year-old woman who had had 3 viable offspring and who had undergone hysterectomy had a 3-year history of mild vaginal prolapse. The condition was not bothersome….

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Racial differences in gestational age–specific neonatal morbidity: further evidence for different gestational lengths

May 23, 2017 by in GYNECOLOGY Comments Off on Racial differences in gestational age–specific neonatal morbidity: further evidence for different gestational lengths

Objective We sought to quantify the gestational age–specific morbidity of black vs white neonates. Study Design This was a population-based retrospective cohort study of singleton live births in Ohio from…

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Delivery of monochorionic twins in the absence of complications: analysis of neonatal outcomes and costs

May 23, 2017 by in GYNECOLOGY Comments Off on Delivery of monochorionic twins in the absence of complications: analysis of neonatal outcomes and costs

Objective We sought to estimate the optimal time to deliver uncomplicated monochorionic-diamnionic (MCDA) twins. Study Design Data were retrospectively obtained from twin pregnancies from 2000 through 2009. The gestational week–specific…

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Glucocorticoid exposure of sheep at 0.7 to 0.75 gestation augments late-gestation fetal stress responses

May 23, 2017 by in GYNECOLOGY Comments Off on Glucocorticoid exposure of sheep at 0.7 to 0.75 gestation augments late-gestation fetal stress responses

Objectives Exposure to glucocorticoid levels inappropriately high for current maturation alters fetal hypothalamo-pituitary-adrenal axis (HPAA) development. In an established fetal sheep model, we determined whether clinical betamethasone doses used to…

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Nonsteroidal antiinflammatory drugs and progestins synergistically enhance cell death in ovarian epithelial cells

May 23, 2017 by in GYNECOLOGY Comments Off on Nonsteroidal antiinflammatory drugs and progestins synergistically enhance cell death in ovarian epithelial cells

Objective There is growing evidence that progestins and nonsteroidal antiinflammatory drugs (NSAIDs) may prevent ovarian cancer. Because both induce apoptosis, we investigated the potential for synergistic impact of combined drug…

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