Protein kinase Cβ2 inhibition reduces hyperglycemia-induced neural tube defects through suppression of a caspase 8-triggered apoptotic pathway

Jun 21, 2017 by in GYNECOLOGY Comments Off on Protein kinase Cβ2 inhibition reduces hyperglycemia-induced neural tube defects through suppression of a caspase 8-triggered apoptotic pathway

Objective Neural tube defects in diabetic embryopathy are associated with increased protein kinase C (PKC)β2 activity and programmed cell death (apoptosis). The apoptosis is triggered by caspase 8, which activates…

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17-hydroxyprogesterone caproate for twin pregnancy: a double-blind, randomized clinical trial

Jun 21, 2017 by in GYNECOLOGY Comments Off on 17-hydroxyprogesterone caproate for twin pregnancy: a double-blind, randomized clinical trial

Objective We sought to determine whether prophylactic treatment with 17-alpha-hydroxyprogesterone caproate (17Pc) in twin pregnancy will reduce neonatal morbidity (primary outcome) by prolonging pregnancy (secondary outcome). Study Design This was…

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Use of the Learning Curve–Cumulative Summation test for quantitative and individualized assessment of competency of a surgical procedure in obstetrics and gynecology: fetoscopic laser ablation as a model

Jun 21, 2017 by in GYNECOLOGY Comments Off on Use of the Learning Curve–Cumulative Summation test for quantitative and individualized assessment of competency of a surgical procedure in obstetrics and gynecology: fetoscopic laser ablation as a model

Objective We sought to determine the learning curve (LC) for fetoscopic laser photocoagulation (FLP) as a model for the evaluation of training in surgical procedures. Study Design A retrospective review…

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