Breath-taking
Case notes A 27-year-old Mennonite woman, gravida 9, para 8, was at 37 weeks of pregnancy when she arrived at labor and delivery complaining of a cough that had worsened…
Discussion: ‘Cost-effectiveness of induced labor’ by Kaimal et al
In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article…
Cost-effectiveness of induced labor: by Kaimal et al
The article below summarizes a roundtable discussion of a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research….
Placental microRNA expression in pregnancies complicated by preeclampsia
Objective The role of posttranscription regulation in preeclampsia is largely unknown. We investigated preeclampsia-related placental microRNA (miRNA) expression using microarray and confirmatory quantitative real-time polymerase chain reaction experiments. Study Design…
A molecular signature of an arrest of descent in human parturition
Objective This study was undertaken to identify the molecular basis of an arrest of descent. Study Design Human myometrium was obtained from women in term labor (TL; n = 29)…
Amniotic fluid levels of glial fibrillary acidic protein in fetal rats with retinoic acid induced myelomeningocele: a potential marker for spinal cord injury
Objective The objective of this study was to determine whether amniotic fluid levels of glial acidic fibrillary protein (GFAP) would reflect myelomeningocele-related neurodegeneration in the rat model of retinoic acid–induced…
Maternal smoking and impaired endothelium-dependent nitric oxide–mediated relaxation of uterine small arteries in vitro
Objective This study aimed to investigate the endothelium-dependent relaxation of uterine small arteries from pregnant nonsmokers, smokers, and ex-smokers who stopped smoking early in pregnancy. Study Design Uterine arteries were…
The effects of postnatal estrogen therapy on brain development in preterm baboons
Objective Estrogen receptors are present within the fetal brain, suggesting that estrogens may exert an influence on cerebral development. Loss of placentally derived estrogen in preterm birth may impair development….
Cost-effectiveness and accuracy of prenatal Down syndrome screening strategies: should the combined test continue to be widely used?
Objective We analyzed the cost-effectiveness (CE) and performances of commonly used prenatal Down syndrome (DS) screening strategies. Study Design We performed computer simulations to compare 8 screening options by applying…
Mesh contraction: myth or reality?
Objective Mesh implants are widely used in surgery for female pelvic organ prolapse. Mesh shrinkage is thought to be common and caused by immunological processes. In this longitudinal study, we…
