Maternal blood mitochondrial DNA content during normal and intrauterine growth restricted (IUGR) pregnancy

Jul 6, 2017 by in GYNECOLOGY Comments Off on Maternal blood mitochondrial DNA content during normal and intrauterine growth restricted (IUGR) pregnancy

Objective We investigated mitochondrial DNA (mtDNA) content in the maternal circulation of normal pregnancies of different gestational ages and in pregnancies complicated by intrauterine growth restriction (IUGR). Study Design We…

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Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction

Jul 6, 2017 by in GYNECOLOGY Comments Off on Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction

Objective Our objective was to determine signaling molecules and apoptosis rate in the term placenta of a baboon model of maternal nutrient reduction (MNR). Study Design Female baboons were fed…

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The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study

Jul 6, 2017 by in GYNECOLOGY Comments Off on The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study

Objective The level of tumor-associated receptor-binding cancer antigen that is expressed on SiSo cells (RCAS1) is decreased significantly in preeclamptic pregnancies. We hypothesized that RCAS1 protein gene silencing might affect…

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Mutations in the hepatocyte nuclear factor-1β( HNF1B)gene are common with combined uterine and renal malformations but are not found with isolated uterine malformations

Jul 6, 2017 by in GYNECOLOGY Comments Off on Mutations in the hepatocyte nuclear factor-1β( HNF1B)gene are common with combined uterine and renal malformations but are not found with isolated uterine malformations

Objective Congenital uterine abnormalities are common and may be associated with developmental renal abnormalities. Mutations of the hepatocyte nuclear factor-1β ( HNF1B) gene are associated with renal and uterine abnormalities….

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A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)

Jul 6, 2017 by in GYNECOLOGY Comments Off on A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)

Objective We sought to determine whether maternal/fetal single-nucleotide polymorphisms (SNPs) in candidate genes are associated with preterm prelabor rupture of membranes (pPROM). Study Design A case-control study was conducted in…

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Longitudinal assessment of bone loss from diagnostic computed tomography scans in gynecologic cancer patients treated with chemotherapy and radiation

Jul 6, 2017 by in GYNECOLOGY Comments Off on Longitudinal assessment of bone loss from diagnostic computed tomography scans in gynecologic cancer patients treated with chemotherapy and radiation

Objective The objective of the study was to measure the volumetric bone mineral density (vBMD) using diagnostic computed tomography scans in gynecologic oncology patients. Study Design In a retrospective study,…

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Posttherapy residual disease associates with long-term survival after chemoradiation for bulky stage 1 Bcervical carcinoma: a Gynecologic Oncology Group study

Jul 6, 2017 by in GYNECOLOGY Comments Off on Posttherapy residual disease associates with long-term survival after chemoradiation for bulky stage 1 Bcervical carcinoma: a Gynecologic Oncology Group study

Objective The objective of the study was to study posttherapy chemoradiation hysterectomy histology with long-term survival in bulky stage 1 B cervical cancer patients. Study Design Gynecologic Oncology Group protocols…

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